Book DescriptionThis volume is the first book to cover the general topic of targeted cancer therapy It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics овьль The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance The particular challenges involved in translating these data to clinical application are discussed This volume should be of broad general interest to researchers and clinicians involved in cancer therapy as well as other scientists interested in current strategies for cancer treatment.  77.7 кв.м.2005 г 303 стр ISBN 3764371749.